Concentrated insulins (where 1mL liquid volume ALWAYS contains more than 100 units of insulin)

• U500 insulin (available as Humulin R in the UK), where 1mL volume = 500 units of insulin
• U300 insulin lantus (available as Toujeo in the UK), where 1mL volume = 300 units of insulin
• U200 insulin degludec (available as Tresiba in the UK), where 1mL volume = 200 units of insulin
• U200 insulin lispro (available as Humalog 200 in the UK), where 1mL volume = 200 units of insulin

Notes:

• These are typically indicated for individuals who require a large amount of insulin to help regulate blood glucose levels (e.g., more than 100 units per day)
• A more concentrated preparation enables a smaller volume of insulin to be injected
• In the UK, Diabetes specialists are often involved when use of these insulins is being considered
• 'Concentrate on Concentration' when prescribing these insulins