Long-Acting analogue (in all cases 1mL liquid volume = 100 units of insulin (U100))

• Insulin glargine (available as Lantus in the UK)
• Insulin detemir (available as Levemir in the UK)

Notes:

• Insulins where the natural amino acid sequence has been modified to promote slower action than with natural insulin
• Either can be used once or twice daily as long acting insulin. Can be taken at any time, but at the same time daily
• Onset of action: Within 30-60 minutes
• Duration of action: 18-24 hours
• All times vary from person to person